Research News

Better healthcare requires better knowledge of the causes of disease, the progression of disease and the response of disease to intervention. Research drives new knowledge and improves patient care. The stories below are just a few of the breakthroughs happening in UHN's labs, research offices and clinics.

UHN Research News

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UHN research news stories

Drs. Gordon Keller, Igor Jurisica, Thomas
Kislinger, Shuzo Sugita, and Elisabeth Tillier,were awarded a total of $3.4-million from the Canada Research Chairs(CRC) program.

Embryonic stem cell biologist and McEwen Centre director Dr. Gordon Keller won a new Tier I CRC, which is awarded to outstanding researchers acknowledged by their peers as world leaders in their fields. Drs. Jurisica, Kislinger and Tillier received new Tier II CRCs --given to exceptional emerging researchers, acknowledged by their peers as having the potential to lead in their field--and Dr. Sugita's existing Tier II CRC was successfully renewed. Drs. Jurisica, Keller and Kislinger were awarded a further $1M in infrastructure funding associated with their CRC awards from the Canada Foundation of Innovation

News Archive [Read all news stories]

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Net Results EXPRESS

mage: NRX Feb 06

Award-winning monthly
e-newsletter of breaking research stories

April 2008

Cardiology: Controlling Cell Growth Cardiology: p27 and CK2alpha are involved in a feedback loop in heart cells

A Canadian-German team led by TGRI's Dr. Rudiger von Harsdorf and colleague Dr. Ludger Hauck have for the first time shown promising parallels between the pathways that control cell enlargement and those that control cell proliferation—the hallmark of cancer.

Cardiac hypertrophy—heart cell enlargement—is common in heart failure patients. It leads to inefficient pumping producing stress on other major organs.....more

Cancer: Predicting Risks in Clinical Trials

Cancer: using individual patient information, physicians can estimate risk using a nomogramJudging the level of risk associated with early phase clinical trials of new anticancer agents is important information for patients and their medical teams.

A new tool developed by an OCI team may make it easier to predict serious adverse effects for individuals seeking entry into trials. A team led by Dr. Lillian Siu analyzed information from 23 phase I and II trials of molecularly targeted anticancer agents to develop a nomogram for the process. A nomogram presents information visually, thus facilitating clinical application and simplifying statistical analysis......more

Read all the stories.

Select an issue from the Net Results EXPRESS archive.

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Net Results

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Quarterly research magazine about the research department at UHN

Inside the Summer 2006 issue

  • Stem Cell Research at UHN
  • Welcome to New OCI Director Dr. Ben Neel
  • Paige's Notes: A New Integrated Approach to Business Development

Read the full issue of Net Results.

Select an issue from the Net Results archive.

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UHN Research Report


UHN produces an annual research report which highlights research accomplishments for the previous fiscal year.

2006 UHN Research Report now available

Four hundred sixty-five researchers, 1,191 publications and an annual budget topping $160M--these are some of the facts and figures about UHN Research highlighted in the 2006 Research Report.

Reports are available for download or in hard copy (e-mail us).


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Did You Know?
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UHN scientists Drs. Ernest McCulloch, James Till (OCI/PMH) and Tak Mak (CFIBCR/OCI/PMH) are three of the four top Canadian scientists honoured for their contributions to cancer research by the Canadian Institutes of Health Research and the Ontario Cancer Research Network.
Drs. McCulloch and Till, recent winners of the 2005 Albert Lasker Award for Basic Medical Research, have published a commentary in the prestigious journal Nature Medicine entitled “Perspectives on the properties of stem cells”.

Toronto Western Research Institute researchers Dr. Andres Lozano and recent PhD graduate Suneil Kalia (TWRI/TWH) reviewed the emerging genetic and cellular discoveries in the area of Parkinson's disease in the July 2005 issue of the journal Scientific American.

A recent international study involving OCI/PMH's Dr. Warren Mason has resulted in the development of a new standard of care for the treatment of glioblastoma, the most deadly form of brain cancer.
Published in the New England Journal of Medicine, the study marks the first advance in treating glioblastoma in 30 years.


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