(April 10, 1997, Toronto) Some patients with enlarged, or dilated, hearts
who desperately need a heart transplant or do not qualify because of medical
reasons are now candidates for a new innovative surgical procedure. Known
as Ventricular Volume Reduction, a portion of the abnormally enlarged heart
is surgically removed to make the heart smaller.
The Toronto Hospital was the first to perform this
procedure in Canada in November, 1996
and has performed five since then.
"There's no question that this is a new surgical treatment for people
with heart failure," says Dr. Robert James Cusimano, a cardiovascular
surgeon at The Toronto Hospital and Assistant Professor, Department of Surgery
at the University of Toronto. "Until now, the only option for these
patients has been heart transplantation when all other medical interventions
failed. But many patients die while waiting for a donor organ, or are not
suitable for transplantation because of other medical conditions."
During the procedure, a portion of the heart muscle from the left ventricle
is removed to make the heart smaller. As a result, the heart is able to
pump blood more easily, and a person's heart failure may improve. Heart
failure is a progressive deterioration of the heart muscle and occurs frequently
following major cardiac injury such as a heart attack. It is the fastest
growing cardiovascular disease due to better treatment of heart attacks
and an aging population. Heart failure affects five per cent of Canadians
and 50 per cent of these die within two to four years of diagnosis.
Ventricular Volume Reduction surgery was first pioneered by Brazilian surgeon,
Randas Batista, who trained in Toronto during the 1970s. Dr. Batista has
performed more than 600 of these procedures. His survival rate at one year
is 65 per cent. Dr. Cusimano visited Dr. Batista while he was in Buffalo
last summer and observed the procedure first hand.
"Technically, this is not a difficult operation. In fact, it's very
similar to a ventricular aneurysm resection where we remove a diseased portion
of the heart that has ballooned out," Dr. Cusimano says. "What
is amazing about the Ventricular Volume Reduction surgery is that this concept
works: patients can have a part of their normal heart muscle removed and
survive the operation."
Dr. Cusimano explains that there is a natural ratio between the radius of
the heart and the heart muscle mass. However, patients with enlarged hearts
have a radius/mass ratio that has been distorted by heart failure, rendering
the heart ineffective in its pumping. The aim of the Ventricular Volume
Reduction is to surgically reduce the size of the heart as close to its
natural radius/mass ratio as possible.
"By reducing the radius of the curvature we are able to reduce the
amount of energy required to pump blood through the heart," Dr. Cusimano
says. "Although the operation does not make the heart any stronger,
it may allow blood to be pumped more efficiently. This will hopefully reduce
the deterioration of heart function, allowing patients to improve."
Following the two-hour procedure, patients remain in hospital approximately
10 days.
Patients will also have their heart rhythms monitored regularly and will
be prescribed anti-arrhythmia medication.
The patients who undergo this procedure will be followed closely. The goal
for surgeons and researchers like Dr. Cusimano is to determine which patients
would make the best candidates for this procedure. "The operation is
not for any heart failure patient," Dr. Cusimano explains. "Our
goal is to determine who is best suited for this procedure and what the
lasting effects and durability of the operation are."
Video Segment
of Procedure
Video downloads:
MPEG format (2m30s, 7 Mb)
AVI format (2m30s, 10 fps, 240x160, 7 Mb)
AVI format (2m30s, 5 fps, 160x120, 2 Mb)
QT format (2m30s, 10 fps, 240x160, 7 Mb)
QT format (2m30s, 5 fps, 160x120, 2 Mb)
For more information, contact Josey Panetta, Senior Media Relations Officer,
The Toronto Hospital, (416) 340-3303